Contact the Medical School’s Office of Communications. It was able to flawlessly (as far as I could see) import any PDF I could throw at it, including things like annotations and fonts. It runs on Linux, Windows, and Mac, and has commercial support. But, still, only a few users have access to the premium feature once they purchase the premium license key. The first proprietary application on this list, Master PDF Editor is an almost perfect drop-in replacement for Adobe Acrobat Pro.
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